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By months three to six, as weight loss accelerates and the medication reaches therapeutic doses, LDL and HDL improvements become more apparent
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For example, in some preclinical and observational studies, liraglutide, one of the most widely used GLP-1 RAs, was associated with an increased incidence of thyroid C-cell hyperplasia and carcinomas, particularly in rodent models, where GLP-1 receptors are more abundantly expressed in thyroid tissue than in humans [15]
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