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Current Evidence: GLP-1 Effects on Rheumatoid Arthritis Symptoms As of 2025, there is limited direct clinical evidence examining the effects of GLP-1 receptor agonists specifically on rheumatoid arthritis symptoms or disease progression
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While both are manufactured by Eli Lilly and both activate the GLP-1 and GIP receptors, retatrutide is a triple agonist that also activates the glucagon receptor
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